Obesity is a complex condition
Obesity is a complex condition
Obesity is a complex condition where excess weight has a negative impact on someone’s physical and psychological health. Excess weight also has an overall impact on someone’s well-being and mobility.
The World Obesity Atlas 2024, published by the World Obesity Federation, predicts that 1.25 billion people globally will be living with obesity by 2030.
Worldwide, at least 2.8 million people die each year because of being overweight or having obesity. Furthermore, an estimated 35.8 million (2.3%) of global DALYs are caused by overweight or obesity [1].
DALYs stands for Disability-Adjusted Life Years, which is a measure of overall disease burden, expressed as the number of years lost due to ill-health, disability, or early death. It is used to assess the impact of different diseases and injuries on a population and to prioritise health interventions.
Related diseases
Diseases and health conditions that are commonly linked to obesity include:
High Blood Pressure
Type 2 Diabetes
Heart Disease
Sleep Apnoea
Reduced Fertility
Diagnosis
To check for obesity, we look at your height and weight to calculate something called your BMI, or Body Mass Index. This gives us a rough idea of whether your weight might be affecting your health.
We might also measure your waist and ask about your daily activity and how you’re feeling emotionally. A BMI over 30, or a waist size above 102 cm (40 inches) for men or 88 cm (34.5 inches) for women, often suggests obesity. But these numbers can vary depending on things like your ethnic background. It’s important to know that BMI is just one tool — it doesn’t tell the whole story.
Your overall health, quality of life, and personal goals matter more. So, we work together to understand your full health picture and make a plan that’s right for you.
Causes of obesity
There are many complex factors that contribute to obesity. Contrary to many misheard beliefs, many of them are difficult or impossible to control.
For example, the hypothalamus is a part of the brain that triggers signals to make you feel hungry and full. The strength and frequency of those signals are things you can’t control.
Genetics can also make you more likely to gain weight, with genetic factors contributing to an estimated 40-70% of variation in body weight. Similarly, hormones from the gut play a key role in regulating body weight, and disruption of those hormones can lead to obesity. These factors can also cause people to regain weight after losing it.
Treatment for obesity
Treatment for obesity
Obesity care and weight loss are not the same. Obesity care delivered by qualified clinicians consists of evidence-based options that address comorbidities of obesity (diabetes, hypertension, hyperlipidemia, etc.) and improve well-being.
Obesity care is about health, not weight. Weight loss is just one outcome of obesity care.
Obesity is a serious, relapsing chronic disease that requires long-term care, just like any other chronic disease. Safe and effective evidence-based obesity treatments that improve patient health are available.
Evidence-based treatments for obesity and severe obesity may include: nutrition and behaviour modification, physical activity, medications, approved devices, and metabolic/bariatric surgery.
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Behavior change treatment intervention can help people lose about 5% of their bodyweight
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Adding medication to these changes can help people lose about 10% to 15% of their bodyweight, but it is important to understand that stopping medication increases the risk of weight returning to pre-treatment levels, and any medication must be continued long-term.
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Surgery can treat those who have significant weight to lose with many losing about 25 to 35% of their body weight within 12 months. Surgery can also help alleviate health conditions such as high blood pressure, type 2 diabetes, and sleep apnea. Patients should ask their doctor to see if they qualify for a referral to a specialist centre for treatment.

A new AI driven web-tool developed by the University of Lille and supported by the SOPHIA project now allows patients and their doctors to accurately predict weight loss over five years following different types of bariatric surgery.
Further information
- Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study – The Lancet Digital Health https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00135-8/fulltext
Addressing Obesity
The growing precedence of obesity is also becoming an increasing concern for policymakers.
They are realising they have a big challenge ahead of them. Pedro Facon, Deputy General Administrator of the Belgian National Institute for Health and Disability Insurance (RIZIV-INAMI-NIHDI) explains.
References
- From https://www.who.int/data/gho/data/themes/topics/topic-details/GHO/body-mass-index
- International Obesity Collaborative Members include the Obesity Action Coalition, OAC; the American Society for Metabolic and Bariatric Surgery, ASMBS; the European Association for the Study of Obesity, EASO; EatRight; The Global Obesity Patient Alliance, GOPA; Obesity Canada; the Obesity Medicine Association; SOPHIA, the Stratification of Obesity Phenotypes to Optimize Future Therapy; the Strategies to Overcome and Prevent Obesity Alliance, STOP; The Obesity Society; the European Coalition for People living with Obesity, ECPO; and the Korean Society for the Study of Obesity, KSSO.